The posterior region of the lens vesicle gives rise to which structure?

• A. Anterior lens epithelium
• B. Posterior cells of lens vesicle
• C. Lens capsule
• D. Corneal endothelium

Answer: (B)

During lens development, the lens vesicle forms from the lens placode and splits its roles between its two surfaces. The cells on the front (anterior wall) become the lens epithelium that lines the anterior surface, while the cells on the back (posterior wall) elongate and differentiate into primary lens fibers, filling the posterior region and making up most of the lens mass. The lens capsule is produced by epithelial cells surrounding the developing lens, and the corneal endothelium originates from neural crest cells migrating into the cornea, not from the lens vesicle. So the posterior region of the lens vesicle specifically gives rise to the posterior cells that become the primary lens fibers.